Ulrike Hubl v2

Ulrike Hubl

Senior Scientist


Protein biochemistry innovations

I moved to New Zealand in 1997 to join the Glycobiology and Enzyme Technology Team (GET) at Industrial Research Limited as a postdoctoral researcher. Since then I have become an integral part of Integrated Biotechnologies, which has now evolved into the Biotechnology group at Callaghan Innovation and continue to work as a Senior Research Scientist in the area of Protein Biochemistry.

Throughout my career, I have had the privilege of working alongside remarkable individuals; one person who stands out for me is Soerge Kelm. During my PhD, I had the privilege of collaborating with him and was consistently amazed by his ability to bridge different aspects of glycobiology. His profound knowledge and its application in research continue to inspire me.

One of my proudest accomplishments was implementing an effective method for analysing multiple whey proteins in a single chromatographic step. This achievement contributed significantly to the biochemistry and purification of milk proteins. 

A crucial insight from my research is the profound impact that even the smallest variation in carbohydrate structures on cell surfaces can have on your health and disease susceptibility.

What invigorates me each day is the possibility of discovering something new and establishing connections between different systems.

Areas of expertise
  • Protein biochemistry, characterization and purification
  • Enzyme technology
  • Biotransformation
  • Oligosaccharide analysis
  • Polysaccharide analysis
  • Glycoproteins and glycopeptides
  • Glycoconjugates
  • Glycolipids
  • Diploma in Chemistry (equivalent to Masters), Christian Albrechts University in Kiel, 1992
  • Doctorate in Natural Sciences (Biochemistry), Christian Albrechts University in Kiel 1996
Selected publications
  • 'Comparison of conditions for the hydrolytic release of N-acetylneuraminic acid from bovine glycomacropeptide.' U.Hubl, and C.Q.Sun, June/July edition of Food NZ, (2022), 22-29.
  • A New Assay for Determining Ganglioside Sialyltransferase Activities lactosylceramide-2,3-sialyl-transferase (SAT I) and monosialylganglioside-2,3-sialyltransferase (SAT IV). Sun,C.Q., Hubl, U., Hoefakker, P., Vasudevamurthy, M.K. and Johnson, K.D. PlosOne PONE-D-13-26796R2 10.1371, 2014.
  • Biotransformation using recombinant CMP sialic acid synthetase and α-2, 6-sialyltransferase: enzymatic synthesis of sialosides.Hubl, U., Sun, C.Q, Zhang, S., Watt, D., Kim, S., Ryan, J. and Johnson, K. Am. J. Biochem. Biotechnol 2012, 8(4), 288 – 303.
  • Milk Sialooligosaccharides: Biological Implications and Purification Strategies. Hubl, U. and Nekrasov, E. In ‘Sialobiology: Structure, Biosynthesis and Function’ (Ed. J. Tiralongo), E. Bentham E-books, Bentham Science Publications, 2012, p.275 – 310.
  • ‘Gangliosides. Nekrasov, E. and Hubl, U. In 'Sialobiology: Structure, Biosynthesis and Function' (Ed. J. Tiralongo), E. Bentham E-books, Bentham Science Publishers, 2012, p. 311 – 379.
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