Downstream processing at scale

Purify, stabilise and concentrate your bioactive compounds for formulation or export. 

Once your extraction, fermentation, or other upstream processes in place, we can support all downstream processing needs to make your product.  

Downstream processing is the process of maximising the recovery and purity of your biological compounds, so the bioactive is ready for formulation. 

As our downstream processing capabilities are co-located with our scale-up fermentation and extraction facilities, we can immediately streamline projects to harvest, separate, concentrate, and isolate your target compounds.   

Scale up with confidence using co-located upstream and downstream facilities

Purify your active compound to target concentration for maximum benefit on the market

Accelerate R&D and de-risk your project with pilot scale access and producing prototype products

Technology transfer of processes

Extensive range of membrane filtration, including coarse dead end, microfiltration, ultrafiltration, nanofiltration, and reverse osmosis, using spiral, tubular, hollow fibre membranes and ceramics. 

Centrifugation, evaporation, and drying

Resin and ion exchanger systems, from bench to 100 L

Large-scale chromatograph, for purification of fine chemicals

Modular bench to pilot scale equipment (1 L to 5,000 L)

Integration with fermentation and extraction processes

Meet our experts

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Abishek Muralidhar Senior Scientist Commercial product development from biotech research

As a Senior Scientist in the Proteins and Enzymes team, my main focus is the development of extraction and purification strategies and analysis of high value proteins and enzymes.

Abishek Muralidhar Senior Scientist

Josiah Doorman Research Technician Protein Purification and Characterisation

I am a Research Technician in the Biotechnologies team, specialising in Biochemistry. My passion for Biochemistry began during my undergraduate degree at the University of Otago, leading me into a Master’s degree with a focus on post-translational modification, specifically ubiquitylation.

Josiah Doorman Research Technician

Craig van Dolleweerd Senior Scientist Using synthetic biology to generate innovative applications

I am a Senior Scientist in the Protein Science & Engineering (PSE) team within the Biotechnologies group. As a molecular biologist, I have worked on bacterial, plant and mammalian recombinant protein expression systems.

Craig van Dolleweerd Senior Scientist

Ulrike Hubl Senior Scientist Protein biochemistry innovations

I moved to New Zealand in 1997 to join the Glycobiology and Enzyme Technology Team (GET) at Industrial Research Limited as a postdoctoral researcher.

Ulrike Hubl Senior Scientist

Cynthia Sun Team Leader, Principal Research Scientist Leading protein and enzyme biotechnology research

I'm currently the Team Leader and Principal Research Scientist in the Proteins and Enzymes team within the Biotechnologies group. I have deep experience and expertise in the field of biochemistry around biotransformation, protein extraction, glycoenzymes and bioassays.

Cynthia Sun Team Leader, Principal Research Scientist

Andrew MacKenzie Distinguished Research Scientist Phospholipid analysis specialist

I am a Principal Research Scientist in the Biotechnologies group where I manage the commercial analytical activities for the Lipids team. During my time at Callaghan Innovation I have established phosphorous-31 nuclear magnetic resonance spectroscopy analysis of phospholipids.

Andrew MacKenzie Distinguished Research Scientist

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Downstream processing at scale

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