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TitleTranslationally related nearly identical molecules: 4-methoxyphenyl 4-O-[6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(fluoren-9-ylmethoxycarbonyl) -α-D-glucopyranosyl]-2-O-benzoyl-3-O-benzyl-6-O-chloroacetyl-β-D- glucopyranoside
Publication TypeJournal Article
Year of Publication2013
AuthorsGainsford, G.J., Schwörer R., and Tyler P.C.
JournalActa Crystallographica Section C: Crystal Structure Communications
Pagination679 - 682
Date Published2013
ISSN01082701 (ISSN)
KeywordsAbsolute configuration, Alzheimer's disease, article, azide, Azides, Benzyl group, chemical structure, conformation, Crystallography, X-Ray, disaccharide, Disaccharides, fluorene derivative, Fluorenes, glucopyranoside, Hydrogen bonds, Molecular Conformation, Molecular Structure, Molecules, Stereoisomerism, synthesis, Title compounds, X ray crystallography
AbstractThe title compound, C59H56ClN3O 16, is an important dissacharide precursor to novel therapeutics for the treatment of Alzheimer's disease. It crystallizes with two independent enantiomerically identical molecules in almost exactly the same orientation in the cell, being one half cell-edge apart. Apart from the conformation of a single benzyl group, the molecules are superimposable. They are bound efficiently using complementary C-H⋯O(carbonyl) hydrogen bonds, principally along the 'duplicating' axis. The absolute configurations were determined. © 2013 International Union of Crystallography.

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