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TitleStrategies for improving fermentation medium performance: A review
Publication TypeJournal Article
Year of Publication1999
AuthorsKennedy, M., and Krouse D.P.
JournalJournal of Industrial Microbiology and Biotechnology
Pagination456 - 475
Date Published1999
ISSN13675435 (ISSN)
Keywordsalgorithm, artificial neural network, culture medium, fermentation, mathematical analysis, microbial growth, model, nonhuman, review, statistical analysis, stoichiometry
AbstractMany techniques are available in the fermentation medium designer's toolbox (borrowing, component swapping, biological mimicry, one-at-a-time, statistical and mathematical techniques - experimental design and optimization, artificial neural networks, fuzzy logic, genetic algorithms, continuous fermentation, pulsed batch and stoichiometric analysis). Each technique has advantages and disadvantages, and situations where they are best applied. No one 'magic bullet' technique exists for all situations. However, considerable advantage can be gained by logical application of the techniques, combined with good experimental design.

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