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TitleSodium hydroxide treatment of PDMS based microfluidic devices
Publication TypeJournal Article
Year of Publication2010
AuthorsHoek, I., Tho F., and Arnold W.M.
JournalLab on a Chip - Miniaturisation for Chemistry and Biology
Pagination2283 - 2285
Date Published2010
ISSN14730197 (ISSN)
Keywordsarticle, dimeticone, flow rate, lab on a chip, microfluidics, oncotic pressure, priority journal, sodium hydroxide, water flow
AbstractWe discuss the use of aqueous NaOH as a facile surface treatment method to control the electroosmotic flow in PDMS microchannels. Flushing of PDMS/PDMS and glass/PDMS microchannels with 1 M NaOH for 24 h leads to a doubling of the electroosmotic flow. This high flow rate is comparable to the flow rates achieved by treating PDMS microchannels with O 2 plasma. Contact angle measurements and ATR-FTIR analysis show that the surface chemistry of the NaOH treated PDMS differs from O 2 plasma treated PDMS. An important advantage of the NaOH treated surfaces is the enhanced stability, irrespective of whether the devices are stored in air or water. © 2010 The Royal Society of Chemistry.

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