Title | Simple synthesis and functionalization of iron nanoparticles for magnetic resonance imaging |
Publication Type | Journal Article |
Year of Publication | 2011 |
Authors | Cheong, S., Ferguson P., Feindel K.W., Hermans I.F., Callaghan P.T., Meyer C., Slocombe A., Su C.-H., Cheng F.-Y., Yeh C.-S., Ingham B., Toney M.F., and Tilley R.D. |
Journal | Angewandte Chemie - International Edition |
Volume | 50 |
Issue | 18 |
Pagination | 4206 - 4209 |
Date Published | 2011 |
ISSN | 14337851 (ISSN) |
Keywords | Animal, Animals, article, chemistry, Contrast Media, contrast medium, Core/shell, Core/shell nanoparticles, diagnostic agent, Facile synthesis, Ferric Compounds, ferric ion, ferric oxide, Functionalizations, Imaging agent, In-vivo, Iron, Iron nanoparticles, Iron oxides, Lead oxide, lymph node, Lymph Nodes, Magnetic resonance imaging, Magnetics, Magnetism, metal nanoparticle, Metal Nanoparticles, Mice, mouse, MRI contrast agents, Nanomagnetics, Nanoparticles, neoplasm, Neoplasms, nuclear magnetic resonance imaging, Oxide nanoparticles, pathology, Resonance, Small tumors, Toxic chemicals, Tumors, ultrastructure |
Abstract | Visualizing small tumors: A novel, facile synthesis leads to the formation of strongly magnetic single-crystal core/shell iron/iron oxide nanoparticles without the use of highly toxic chemicals. The core/shell nanoparticles are highly effective MRI contrast agents and enable unambiguous detection of small tumors of 1-3 mm in vivo (see picture). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
URL | http://www.scopus.com/inward/record.url?eid=2-s2.0-79955386245&partnerID=40&md5=31bd7277b670b0cccd0fba1e130a793f |
DOI | 10.1002/anie.201100562 |