Callaghan Innovation Research Papers

Back to Research Papers

TitleSimple synthesis and functionalization of iron nanoparticles for magnetic resonance imaging
Publication TypeJournal Article
Year of Publication2011
AuthorsCheong, S., Ferguson P., Feindel K.W., Hermans I.F., Callaghan P.T., Meyer C., Slocombe A., Su C.-H., Cheng F.-Y., Yeh C.-S., Ingham B., Toney M.F., and Tilley R.D.
JournalAngewandte Chemie - International Edition
Pagination4206 - 4209
Date Published2011
ISSN14337851 (ISSN)
KeywordsAnimal, Animals, article, chemistry, Contrast Media, contrast medium, Core/shell, Core/shell nanoparticles, diagnostic agent, Facile synthesis, Ferric Compounds, ferric ion, ferric oxide, Functionalizations, Imaging agent, In-vivo, Iron, Iron nanoparticles, Iron oxides, Lead oxide, lymph node, Lymph Nodes, Magnetic resonance imaging, Magnetics, Magnetism, metal nanoparticle, Metal Nanoparticles, Mice, mouse, MRI contrast agents, Nanomagnetics, Nanoparticles, neoplasm, Neoplasms, nuclear magnetic resonance imaging, Oxide nanoparticles, pathology, Resonance, Small tumors, Toxic chemicals, Tumors, ultrastructure
AbstractVisualizing small tumors: A novel, facile synthesis leads to the formation of strongly magnetic single-crystal core/shell iron/iron oxide nanoparticles without the use of highly toxic chemicals. The core/shell nanoparticles are highly effective MRI contrast agents and enable unambiguous detection of small tumors of 1-3 mm in vivo (see picture). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Back to top