| Title | New polar steroids from the sponges Trachyopsis halichondroides and Cymbastela coralliophila |
| Publication Type | Journal Article |
| Year of Publication | 1995 |
| Authors | Makarieva, T.N., Stonik V.A., Dmitrenok A.S., Krasokhin V.B., Svetashev V.I., and Vysotskii M.V. |
| Journal | Steroids |
| Volume | 60 |
| Issue | 4 |
| Pagination | 316 - 320 |
| Date Published | 1995 |
| ISSN | 0039128X (ISSN) |
| Keywords | 23,24 dinor 5alpha cholane 2beta,3alpha,6alpha triol, 24 isopropyl 5alpha cholestane 2beta,3alpha,6alpha triol, 5alpha cholest 22 ene 2beta,3alpha,6alpha triol, 5alpha pregnane 2beta,3alpha,6alpha triol, Acetates, acetylation, Animals, article, biosynthesis, column chromatography, Coralliophila, Cymbastela coralliophila, gas liquid chromatography, high performance liquid chromatography, Hydrolysis, hydroxysteroid, Magnetic Resonance Spectroscopy, nonhuman, nuclear magnetic resonance, Porifera, sponge (porifera), steroid, Steroids, sulfate, Sulfates, thin layer chromatography, unclassified drug |
| Abstract | Fractions of trisulfated trihydroxysteroids from the sponges Trachyopsis halichondroides (two different collections) and Cymbastela coralliophila have been isolated and investigated. Ten triacetates were obtained from these fractions by desulfatation/acetylation followed by chromatographic separation, and their structures have been established. Four of these derivatives-namely, triacetates of 5α-pregnance-2β,3α,6α-triol (3c), 23,24-dinor-5α-cholane-2β,3α,6α-triol (4c), 5α-cholest-22-ene-2β,3α,6α-triol (7c), and 24-isopropyl-5α-cholestane-2β,3α,6α-triol (11c)-are described as new derivatives of natural steroids. © 1995. |
| URL | http://www.scopus.com/inward/record.url?eid=2-s2.0-0029001041&partnerID=40&md5=b386e0c74686bef4c822074626c007b5 |
| DOI | 10.1016/0039-128X(94)00056-I |
