Callaghan Innovation Research Papers

Back to Research Papers

TitleThe effect of long-chain N-acylethanolamines on some membrane-associated functions of neuroblastoma C1300 N18 cells
Publication TypeJournal Article
Year of Publication1993
AuthorsGulaya, N.M., Melnik A.A., Balkov D.I., Volkov G.L., Vysotskiy M.V., and Vaskovsky V.E.
JournalBBA - Biomembranes
Pagination280 - 288
Date Published1993
ISSN00052736 (ISSN)
Keywordsarticle, Biological Transport, cell membrane, Cell Membrane Permeability, controlled study, Ethanolamines, human, human cell, Lipids, Lysophospholipids, n acylethanolamine, neuroblastoma, neuroblastoma cell, Phosphatidylethanolamines, priority journal, sodium channel, Sodium Channels, Tumor Cells, Cultured, unclassified drug, veratridine
AbstractAs reported earlier (Gulaya, N.M., Vaskovsky, V.E., Vysotsky, M.V., Volkov, G.L., Govseeva, N.N. and Artemenko, I.P. (1988) Ukr. Biochim. J. 60, 58-63), N-acylphosphatidylethanolamines (NAPE) and products of their catabolism, N-acylethanolamines (NAE), are present in the lipids of neuroblastoma C1300 N18 undifferentiated cells. The present paper describes the distribution of NAE added to culture medium of differentiated cells and its effect on the fast sodium channels and some other membrane characteristics. It is shown that NAE inhibits the destroying action of veratridine on membranes. © 1993.

Back to top