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TitleCrystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase 2 from Arabidopsis thaliana
Publication TypeJournal Article
Year of Publication2011
AuthorsGriffin, M.D.W., Billakanti J.M., Gerrard J.A., Dobson R.C.J., and Pearce F.G.
JournalActa Crystallographica Section F: Structural Biology and Crystallization Communications
Pagination1386 - 1390
Date Published2011
ISSN17443091 (ISSN)
KeywordsAnimalia, Arabidopsis, Arabidopsis thaliana, article, chemistry, Crystallization, Crystallography, X-Ray, dihydrodipicolinate synthase, enzymology, Hydro-Lyases, hydrolyase, X ray crystallography
AbstractDihydrodipicolinate synthase (DHDPS; EC catalyzes the first committed step of the lysine-biosynthetic pathway in plants and bacteria. Since (S)-lysine biosynthesis does not occur in animals, DHDPS is an attractive target for rational antibiotic and herbicide design. Here, the cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of DHDPS2 from Arabidopsis thaliana are reported. Diffraction-quality protein crystals belonged to space group P21212. © 2011 International Union of Crystallography. All rights reserved.

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